HOW TO EXCLUDE SEVERAL PC FROM SCCM APPLICATION DEPLOYMENT.

1. You need to create new "exclude collection" and dump all the PCs that you want to exclude.
2. After finish created the "exclude collection".  Select the existing application deployment collection and right click choose Properties.
3. On the group Properties, select Membership Rules. 
4. On the Membership Rules, click Add Rule and select Exclude Collections.
5. Select the exclude collection and click Ok.
6. On the membership rules, you will see the exclusion details.  Click Apply and Ok to proceed.
7. Done.

Notes: All the changes settings above are performed on the SCCM 2012 r2 console > Assets and Compliance > Devices.